Endocrine Abstracts

Introduction: Polycystic ovary syndrome (PCOS) is a common endocrinopathy associated with increased cardiovascular risk in reproductive aged women. Circulating osteoprotegerin (OPG) and soluble receptor activator of nuclear factor κB ligand (sRANKL) are associated with subclinical atherosclerosis. Our aim is to evalutate serum OPG and sRANKL levels and their relations with cardiovascular and metabolic markers in paients with obese and non-obese PCOS.<p class="abstext"...

Introduction: Patients with parathyroid carcinoma (PCA) and synchronous disease in other parathyroid glands have been reported in the literature. Here, we report a patient who had persistant hypercalcemia after operated from parathyroid carcinoma and improvement of hypercalcemia after the subsequent operation from atypically localised parathyroid adenoma.Case report: A 62-year-old man presented with a history of headache, fatigue, and nervousness. Labora...

Background: Primary hyperparathyroidism (PHPT) is one of the most common endocrine diseases. Parathyroid carcinoma, a rare entity, comprises a small percentage of patients with hyperparathyroidism and represents 0.005% of all cancers and <1% of cases of PHPT.Material and methods: Patients was diagnosed at the Endocrinology Department of Diskapi Yildirim Beyazit Training and Research Hospital between 2010 and 2016. Ultrasound and 99mTc-Sestamibi confi...

Introduction: Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders among women of reproductive age. A disintegrin and metalloproteinase with thrombospondin-like motifs (ADAMTS) are involved in inflammation and fertility. The aim of this investigation was to evaluate to serum levels of ADAMTS1, ADAMTS5, ADAMTS9, IL17, IL23, IL33 and to find out the relationship between these inflammatory cytokines and ADAMTSs in PCOS patients.Met...

Introduction: Vitamin D deficiency is a common health problem. Vitamin D supplements are used to improve vitamin D status. However, there are few data about what doses to give and how often to give. The aim of this study is to determine the effects of single high dose or daily low dose oral cholecalciferol (vitamin D3) on vitamin D levels and muscle strenght.Methods and design: 60 healthy postmenouposal women who had serum vitamin D levels wer...

Introduction: Hypopituitarism is commonly acquired in adult life and its main causes are pituitary tumors and/or their treatments, empty sella syndrome and etc.Patients and methods: A double centre, cross-sectional database study was performed in Turkish population for last 10 years to investigate the etiology of hypopituitarism. One-hundred forty nine patients were included (53% female and 47% male) with a mean age of 47.9±15.6 years (ranging from ...

Introduction: The relationship between hyperthyroidism and voice disorders has not been identified before. The aim of this study was to investigate the changes in the acoustic values in patients with subclinical thyrotoxicosis.Methods: In this study, acoustic voice analysis was evaluated in a total of 115 cases. Sixty of 115 individuals (18 men and 42 women) had subclinical thyrotoxicosis, aged between 18 and 65 years, and all had no history of laryngeal...

Aims: Primary hyperparathyroidism (PH) has been reported to be associated with increased insulin resistance, hypertension, dyslipidemia and cardiovascular inflammatory markers. The aims of this study were to evaluate the rate of metabolic syndrome (MS) and effect of parathormone, calcium and phosphorus levels to MS components in PH subjects.Methods: One hundred and fifty one subjects, 23 men and 128 women, aged 53±11.2 years with newly diagnosed PH ...

Introduction: Paragangliomas are neuroendocrine tumors arising from extra-adrenal chromaffin cells. Paragangliomas of the head and neck frequently originate from the paraganglionic system including the carotid bifurcation, middle ear and the ganglion nodosum of the vagus nerve. However, of paragangliomas of the head and neck, only 1–3% secrete hormones and majority are non-functional. Here, we describe a case of non-functional paraganglioma confused with parathyroid adeno...

Aim: Cardiac rhythm abnormalities have been documented in acromegalic patients. Our aim is to evaluate atrial electromechanical delay (EMD) with tissue doppler imaging (TDI) in patients with acromegaly.Material and methods: Fourty patients with acromegaly (13 patients with remission disease and 27 patients with active disease; 22 women and 18 men; mean aged 46.1±10.3 years), and 37 age- and sex-matched healthy controls were enrolled in the study. At...